Article
Association study of three polymorphisms of kinesin light-chain 1 gene with Alzheimer's disease.
Neuroscience letters - 30 Sept 2004
Dhaenens Claire-Marie, Van Brussel Edwige, Schraen-Maschke Susanna, Pasquier Florence, Delacourte André, Sablonnière Bernard
Abstract excerpt
The transport of amyloid precursor protein is mediated through its interaction with kinesin light-chain 1 (KNS2). We hypothesized that kinesin light-chain dysfunction might be involved in the pathogenesis of Alzheimer's disease (AD). To assess the physiological relevance of an allelic variation i...
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