Article
Evaluation of the roles of the A185C and C406T kinesin light-chain 1 variants in the development of leukoaraiosis.
Neuroscience letters - 18 Dec 2007
Szolnoki Zoltan, Kondacs Andras, Mandi Yvette, Somogyvari Ferenc
Abstract excerpt
Vascular white matter demyelinization of the brain is referred to as leukoaraiosis (LA). This frequent age-associated entity leads to a cognitive decline or dementia. The background of LA has been hypothesized to be a chronic hypoxia-induced functional cytoskeleton malfunction. Setting out from this assumption, we earlier found that the kinesin light-chain 1 (KNS2) cytoskeleton motor protein 56836CC single...
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