Article

KIF5A and KLC1 expression in Alzheimer’s disease: relationship and genetic influences

2019-06-26

Abstract excerpt

<h4>Background: </h4> Early disturbances in axonal transport, before the onset of gross neuropathology, occur in a spectrum of neurodegenerative diseases including Alzheimer’s disease. Kinesin superfamily motor proteins (KIFs) are responsible for anterograde protein transport within the axon of various cellular cargoes, including synaptic and structural proteins. Dysregulated KIF expression has been associated wit...

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Literature Corpus work: 5d86a804-2063-56bd-8cbd-3140b751a973
DOI: 10.12688/amrcopenres.12861.2

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