Article
Genetic studies in relation to kuru: an overview.
Current molecular medicine - 1 Jun 2004
Goldfarb L G, Cervenakova L, Gajdusek D C
Abstract excerpt
Kuru is a subacute neurodegenerative disease presenting with limb ataxia, dysarthria, and a shivering tremor. The disease progress to complete motor and mental incapacity and death within 6 to 24 months. Neuropathologically, a typical pattern of neuronal loss, astrocytic and microglial proliferation, characteristic "kuru-type" amyloid plaques, and PrP deposits in the cerebral cortex and cerebellum are observed....
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