Article
Genetic susceptibility, evolution and the kuru epidemic.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Nov 2008
Mead Simon, Whitfield Jerome, Poulter Mark, Shah Paresh, Uphill James, Beck Jonathan, Campbell Tracy, Al-Dujaily Huda, Hummerich Holger, Alpers Michael P, Collinge John
Abstract excerpt
The acquired prion disease kuru was restricted to the Fore and neighbouring linguistic groups of the Papua New Guinea highlands and largely affected children and adult women. Oral history documents the onset of the epidemic in the early twentieth century, followed by a peak in the mid-twentieth century and subsequently a well-documented decline in frequency. In the context of these strong associations (gender,...
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