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Article

Increased susceptibility to Kuru of carriers of the PRNP 129 methionine/methionine genotype.

The Journal of infectious diseases - 15 Jan 2001

Lee H S, Brown P, Cervenáková L, Garruto R M, Alpers M P, Gajdusek D C, Goldfarb L G

Abstract excerpt

Kuru reached epidemic proportions by the mid-twentieth century among the Fore people of New Guinea and disappeared after the abolition of cannibalistic rituals. To determine susceptibility to kuru and its role in the spread and elimination of the epidemic, we analyzed the PRNP gene coding sequences in 5 kuru patients; no germline mutations were found. Analysis of the PRNP 129 methionine (M)/valine (V)...

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Identifiers

PMID: 11120925
DOI: 10.1086/317935

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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