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Article

A novel protective prion protein variant that colocalizes with kuru exposure.

The New England journal of medicine - 19 Nov 2009

Mead Simon, Whitfield Jerome, Poulter Mark, Shah Paresh, Uphill James, Campbell Tracy, Al-Dujaily Huda, Hummerich Holger, Beck Jon, Mein Charles A, Verzilli Claudio, Whittaker John, Alpers Michael P, Collinge John

Abstract excerpt

BACKGROUND: Kuru is a devastating epidemic prion disease that affected a highly restricted geographic area of the Papua New Guinea highlands; at its peak, it predominantly affected adult women and children of both sexes. Its incidence has steadily declined since the cessation of its route of tran...

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Identifiers

PMID: 19923577
DOI: 10.1056/NEJMoa0809716

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PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19923577-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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