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Article

Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway.

Biochemical and biophysical research communications - 8 Oct 2004

Parker Monica, Roberts Richard, Enriquez Miriam, Zhao Xia, Takahashi Takamune, Pat Cerretti Douglas, Daniel Tom, Chen Jin

Abstract excerpt

Eph/ephrin receptors and ligands mediate cell-cell interaction through reciprocal signaling upon juxtacrine contact, and play a critical role in embryonic patterning, neuronal targeting, and vascular assembly. To study transmembrane ephrin-B ligand trafficking, we determined the cellular localization of ephrin-B1-GFP upon engagement by EphB1. Under normal culture conditions ephrin-B1-GFP is localized to the...

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Identifiers

PMID: 15351694
DOI: 10.1016/j.bbrc.2004.07.209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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