Article
Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis.
Journal of cell science - 1 Aug 2002
Huynh-Do Uyen, Vindis Cécile, Liu Hua, Cerretti Douglas Pat, McGrew Jeffrey T, Enriquez Miriam, Chen Jin, Daniel Thomas O
Abstract excerpt
Ephrin-B/EphB family proteins are implicated in bidirectional signaling and were initially defined through the function of their ectodomain sequences in activating EphB receptor tyrosine kinases. Ephrin-B1-3 are transmembrane proteins sharing highly conserved C-terminal cytoplasmic sequences. Here we use a soluble EphB1 ectodomain fusion protein (EphB1/Fc) to demonstrate that ephrin-B1 transduces signals that...
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