Article
Molecular mechanism and physiological functions of clathrin-mediated endocytosis.
Nature reviews. Molecular cell biology - 22 Jul 2011
McMahon Harvey T, Boucrot Emmanuel
Abstract excerpt
Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission, signal transduction and the regulation of many plasma membrane activities and is thus essential to higher eukaryotic life. Morphological stages of vesicle formation are mirrored by progression through various protein modules...
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