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Article

Ephrin-B2 controls PDGFRβ internalization and signaling.

Genes & development - 1 Dec 2013

Nakayama Akiko, Nakayama Masanori, Turner Christopher J, Höing Susanne, Lepore John J, Adams Ralf H

Abstract excerpt

B-class ephrins, ligands for EphB receptor tyrosine kinases, are critical regulators of growth and patterning processes in many organs and species. In the endothelium of the developing vasculature, ephrin-B2 controls endothelial sprouting and proliferation, which has been linked to vascular endothelial growth factor (VEGF) receptor endocytosis and signaling. Ephrin-B2 also has essential roles in supporting mural...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myocytes, Smooth Muscle

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Share to Receptor, Platelet-Derived Growth Factor beta

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Source

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Identifiers

PMID: 24298057
DOI: 10.1101/gad.224089.113
PMCID: PMC3861671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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