Article

EPH Receptor Tyrosine Kinases Regulate Epithelial Morphogenesis and Phosphorylate the PAR-3 Scaffold Protein to Modulate Downstream Signaling Networks

2020-09-07

Abstract excerpt

<h4>SUMMARY</h4> The EPH family is the largest among receptor tyrosine kinases (RTKs) in humans. In contrast to other RTKs, EPH receptors (EPHRs) cognate ligands, ephrins, are tethered to the cell surface. This results in EPHR-ephrin signaling being mainly involved in short-range cell-cell communication events that regulate cell adhesion, migration and tissue boundary formation. Although EPHRs functions have been...

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Literature Corpus work: eafc299f-4267-5c61-a90f-c9b77fd44da9
DOI: 10.1101/2020.09.06.285270

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