Article
Host range mutants of v-src: alterations in kinase activity and substrate interactions.
Journal of virology - 1 Jul 1992
Liebl E C, England L J, DeClue J E, Martin G S
Abstract excerpt
Host range mutants of Schmidt-Ruppin v-src that transform chicken embryo fibroblasts (CEF) but not Rat-2 cells were generated previously by linker insertion-deletion mutagenesis (J. E. DeClue and G. S. Martin, J. Virol. 63:542-554, 1989). One of these mutants, SRX5, in which Tyr-416 is substitute...
Topics
- Amino Acid Sequence
- Animals
- Annexins
- Calcium-Binding Proteins
- Cell Line
- Chick Embryo
- Cloning, Molecular
- Gene Expression
- Immunoblotting
- Molecular Sequence Data
- Mutation
- Oncogene Protein pp60(v-src)
- Phenotype
- Phosphorylation
- Protein Kinases
- Rats
- Substrate Specificity