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Article

Role of the HLA-DP Glu 69 and the TNF-alpha TNF-alpha 2 gene markers in susceptibility to beryllium hypersensitivity.

International journal of immunopathology and pharmacology - 1 Jan 2000

Rogliani P, Amicosante M, Berretta F, Dotti C, Bocchino M, O'Donnell K M, Saltini C

Abstract excerpt

Berylliosis is an environmental chronic inflammatory disorder of the lung caused by inhalation of beryllium dusts, characterized by the accumulation of CD4+ T cells and macrophages in the lower respiratory tract. Beryllium presentation to CD4+ T cells from patients with berylliosis results in T c...

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Identifiers

PMID: 15345185
DOI: 10.1177/03946320040170S202

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15345185-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Role of the HLA-DP Glu 69 and the TNF-alpha TNF-alpha 2 gene markers in susceptibility to beryllium hypersensitivity.PMID 15345185Read ↗

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HLA-DP allele-specific T cell responses to beryllium account for DP-associated susceptibility to chronic beryllium disease.Semantic proximity Read ↗

High beryllium-stimulated TNF-alpha is associated with the -308 TNF-alpha promoter polymorphism and with clinical severity in chronic beryllium disease.Semantic proximity Read ↗

Identification of HLA-DRPhebeta47 as the susceptibility marker of hypersensitivity to beryllium in individuals lacking the berylliosis-associated supratypic marker HLA-DPGlubeta69.Semantic proximity Read ↗

HLA-DPB1 and chronic beryllium disease: a HuGE review.Semantic proximity Read ↗

Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation.Semantic proximity Read ↗

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