Article
Major histocompatibility locus genetic markers of beryllium sensitization and disease.
The European respiratory journal - 1 Oct 2001
Saltini C, Richeldi L, Losi M, Amicosante M, Voorter C, van den Berg-Loonen E, Dweik R A, Wiedemann H P, Deubner D C, Tinelli C
Abstract excerpt
Hypersensitivity to beryllium (Be) is found in 1-16% of exposed workers undergoing immunological screening for beryllium disease using the beryllium lymphocyte proliferation test (BeLPT). However, only approximately 50% of BeLPT-positive workers present with lung granulomas (i.e. berylliosis). As berylliosis is associated with the human leukocyte antigen (HLA)-DP supratypic marker DPGlu69, the authors asked...
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