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Article

TNF-alpha polymorphisms in chronic beryllium disease and beryllium sensitization.

Journal of occupational and environmental medicine - 1 Apr 2007

McCanlies Erin C, Schuler Christine R, Kreiss Kathleen, Frye Bonnie L, Ensey James S, Weston Ainsley

Abstract excerpt

OBJECTIVE: Tumor necrosis factor-alpha (TNF-alpha) is a potent cytokine involved in normal immune functions. The aim of this study was to investigate if there is an association between chronic beryllium disease or beryllium sensitization and two variants of the TNF-alpha gene located at -308 and -238 called TNF-alpha-308*02 and TNF-alpha-238*02. METHODS: TNF-alpha-308 and TNF-alpha-238 genotyping was conducted in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17426528
DOI: 10.1097/JOM.0b013e31803b9499

Genes

TNF

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