Article
Hypercholesterolemia in ENU-induced mouse mutants.
Journal of lipid research - 1 Nov 2004
Mohr Manuela, Klempt Martina, Rathkolb Birgit, de Angelis Martin Hrabé, Wolf Eckhard, Aigner Bernhard
Abstract excerpt
Hypercholesterolemia is caused by multiple environmental factors and genetic predispositions, and plays an important role in the development and pathogenesis of various human diseases. In this study, we aimed to establish randomly mutant mouse lines showing hypercholesterolemia for their further use in the detection of novel causative alleles. In the Munich ENU Mouse Mutagenesis Project, clinical chemistry blood...
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