Article
Quantification of helix-helix binding affinities in micelles and lipid bilayers.
Protein science : a publication of the Protein Society - 1 Oct 2004
Lomize Andrei L, Pogozheva I D, Mosberg H I
Abstract excerpt
A theoretical approach for estimating association free energies of alpha-helices in nonpolar media has been developed. The parameters of energy functions have been derived from DeltaDeltaG values of mutants in water-soluble proteins and partitioning of organic solutes between water and nonpolar solvents. The proposed approach was verified successfully against three sets of published data: (1) dissociation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
