Position-dependence of stabilizing polar interactions of asparagine in transmembrane helical bundles.

Abstract excerpt

Recent studies with model peptides and statistical analyses of the crystal structures of membrane proteins have shown that buried polar interactions contribute significantly to the stabilization of the three-dimensional structures of membrane proteins. Here, we probe how the location of these polar groups along the transmembrane helices affect their free energies of interaction. Asn residues were placed singly...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acids
• Share to Asparagine
• Share to Dimerization