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Article

Asparagine-mediated self-association of a model transmembrane helix.

Nature structural biology - 1 Feb 2000

Choma C, Gratkowski H, Lear J D, DeGrado W F

Abstract excerpt

In membrane proteins, the extent to which polarity, hydrogen bonding, and van der Waals packing interactions of the buried, internal residues direct protein folding and association of transmembrane segments is poorly understood. The energetics associated with these various interactions should differ substantially between membrane versus water-soluble proteins. To help evaluate these energetics, we have altered a...

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PMID: 10655620
DOI: 10.1038/72440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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