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Article

Free energy of burying hydrophobic residues in the interface between protein subunits.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 1998

Vallone B, Miele A E, Vecchini P, Chiancone E, Brunori M

Abstract excerpt

We have obtained an experimental estimate of the free energy change associated with variations at the interface between protein subunits, a subject that has raised considerable interest since the concept of accessible surface area was introduced by Lee and Richards [Lee, B. & Richards, F. M. (1971) J. Mol. Biol. 55, 379-400]. We determined by analytical ultracentrifugation the dimer-tetramer equilibrium constant...

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Identifiers

PMID: 9600924
DOI: 10.1073/pnas.95.11.6103
PMCID: PMC27592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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