Article
Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1.
The Journal of biological chemistry - 19 Nov 2004
Radhika V, Onesime Djamila, Ha Ji Hee, Dhanasekaran N
Abstract excerpt
Galpha13, the alpha-subunit of the heterotrimeric G protein G13, has been shown to stimulate cell migration in addition to inducing oncogenic transformation. Cta, a Drosophila ortholog of G13, has been shown to be critical for cell migration leading to the ventral furrow formation in Drosophila embryos. Loss of Galpha13 has been shown to disrupt cell migration associated with angiogenesis in developing mouse...
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