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Regulation of cancer cell motility through actin reorganization

1 Jul 2005

Abstract excerpt

Cell migration is a critical step in tumor invasion and metastasis, and regulation of this process will lead to appropriate therapies for treating cancer. Cancer cells migrate in various ways, according to cell type and degree of differentiation. The different types of cell migration are regulated by different mechanisms. Reorganization of the actin cytoskeleton is the primary mechanism of cell motility and is...

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PMID: 16053508
DOI: 10.1111/j.1349-7006.2005.00062.x

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