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Article

G proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal ruffles.

The Journal of biological chemistry - 27 Oct 2006

Wang Dawei, Tan Ying-cai, Kreitzer Geri E, Nakai Yoko, Shan Dandan, Zheng Yi, Huang Xin-Yun

Abstract excerpt

Growth factors induce massive actin cytoskeletal remodeling in cells. These reorganization events underlie various cellular responses such as cell migration and morphological changes. One major form of actin reorganization is the formation and disassembly of dorsal ruffles (also named waves, dorsal rings, or circular ruffles). Dorsal ruffles are involved in physiological functions including cell migration,...

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PMID: 16943201
DOI: 10.1074/jbc.M604588200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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