Article
Tests for establishing compatibility of an observed genotype distribution with Hardy-Weinberg equilibrium in the case of a biallelic locus.
Biometrics - 1 Sept 2004
Wellek Stefan
Abstract excerpt
The classical chi(2)-procedure for the assessment of genetic equilibrium is tailored for establishing lack rather than goodness of fit of an observed genotype distribution to a model satisfying the Hardy-Weinberg law, and the same is true for the exact competitors to the large-sample procedure, which have been proposed in the biostatistical literature since the late 1930s. In this contribution, the methodology of...
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