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Article

Tests for establishing compatibility of an observed genotype distribution with Hardy-Weinberg equilibrium in the case of a biallelic locus.

Biometrics - 1 Sept 2004

Wellek Stefan

Abstract excerpt

The classical chi(2)-procedure for the assessment of genetic equilibrium is tailored for establishing lack rather than goodness of fit of an observed genotype distribution to a model satisfying the Hardy-Weinberg law, and the same is true for the exact competitors to the large-sample procedure, which have been proposed in the biostatistical literature since the late 1930s. In this contribution, the methodology of...

Topics

Alleles
Alzheimer Disease
Biometry
Fibronectins
Gene Frequency
Genotype
Heterozygote
Humans
Methyltransferases
Models, Genetic
Models, Statistical
Phosphatidylethanolamine N-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Schizophrenia

Tyrosine 3-Monooxygenase

Source

Identifiers

PMID: 15339292
DOI: 10.1111/j.0006-341X.2004.00219.x

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