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Article

An unconditional exact test for the Hardy-Weinberg equilibrium law: sample-space ordering using the Bayes factor.

Genetics - 1 Jun 2001

Montoya-Delgado L E, Irony T Z, de B Pereira C A, Whittle M R

Abstract excerpt

Much forensic inference based upon DNA evidence is made assuming that the Hardy-Weinberg equilibrium (HWE) is valid for the genetic loci being used. Several statistical tests to detect and measure deviation from HWE have been devised, each having advantages and limitations. The limitations become more obvious when testing for deviation within multiallelic DNA loci is attempted. Here we present an exact test for...

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Identifiers

PMID: 11404348
DOI: 10.1093/genetics/158.2.875
PMCID: PMC1461670

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