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Article

Graphical tests for Hardy-Weinberg equilibrium based on the ternary plot.

Human heredity - 1 Jan 2008

Graffelman Jan, Camarena Jair Morales

Abstract excerpt

OBJECTIVE: We design a graphical test for Hardy-Weinberg equilibrium. This can circumvent the calculation of p values and the statistical (non)significance of a large number of bi-allelic markers can be inferred from their position in a graph. METHOD: By rewriting expressions for the chi(2) statistic (with and without continuity correction) in terms of the heterozygote frequency an acceptance region for...

Topics

Chromosomes, Human, Pair 22
Gene Frequency
Genotype
Heterozygote
Humans
Linkage Disequilibrium
Models, Genetic
Models, Statistical
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 17898538
DOI: 10.1159/000108939

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