Article
Graphical tests for Hardy-Weinberg equilibrium based on the ternary plot.
Human heredity - 1 Jan 2008
Graffelman Jan, Camarena Jair Morales
Abstract excerpt
OBJECTIVE: We design a graphical test for Hardy-Weinberg equilibrium. This can circumvent the calculation of p values and the statistical (non)significance of a large number of bi-allelic markers can be inferred from their position in a graph. METHOD: By rewriting expressions for the chi(2) statistic (with and without continuity correction) in terms of the heterozygote frequency an acceptance region for...
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