Article
Testing heterozygote excess and deficiency.
Genetics - 1 Aug 1995
Rousset F, Raymond M
Abstract excerpt
Currently used tests of Hardy-Weinberg proportions do not take into account the nature of the alternative hypothesis, which is generally a heterozygote deficiency. Different exact tests, appropriate for small sample size and large number of alleles, are proposed in this perspective, and their properties are evaluated by power comparisons. Some tests are found to be close to optimal for the detection of inbreeding...
Topics
- Alleles
- Crosses, Genetic
- Genetics, Population
- Heterozygote
- Models, Genetic
- Statistics as Topic