Hardy-Weinberg equilibrium diagnostics.

doi:10.1006/tpbi.2002.1613

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Article

Hardy-Weinberg equilibrium diagnostics.

Theoretical population biology - 1 Nov 2002

Rogatko André, Slifker Michael J, Babb James S

Abstract excerpt

We propose two diagnostics for the statistical assessment of Hardy-Weinberg equilibrium. One diagnostic is the posterior probability of the complement of the smallest highest posterior density credible region that includes points in the parameter space consistent with the hypothesis of equilibrium. The null hypothesis of equilibrium is to be rejected if this probability is less than a pre-selected critical level....

Topics

Alleles
Bayes Theorem
Chromosomes, Human, X
Gene Frequency
Genetic Diseases, Inborn
Genetic Linkage
Genotype
Humans
Models, Theoretical

Source

Open in PubMed

Identifiers

PMID: 12408944
DOI: 10.1006/tpbi.2002.1613

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