Article
Brain-derived neurotrophic factor, apolipoprotein E genetic variants and cognitive performance in Alzheimer's disease.
Neuroscience letters - 9 Sept 2004
Nacmias Benedetta, Piccini Carolina, Bagnoli Silvia, Tedde Andrea, Cellini Elena, Bracco Laura, Sorbi Sandro
Abstract excerpt
Since greater attention has been paid to the direct link of genetic variation to cognition and memory performance, apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) have been the two most frequently studied genes. To investigate the effect of BDNF and ApoE polymorphisms on the cognitive profile of mild-moderate Alzheimer's disease (AD) cases, AD patients, genotyped for ApoE and BDNF...
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