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Article

DNase1 exon2 analysis in Tunisian patients with rheumatoid arthritis, systemic lupus erythematosus and Sjögren syndrome and healthy subjects.

Rheumatology international - 1 Nov 2009

Belguith-Maalej Salima, Hadj-Kacem Hassen, Kaddour Neila, Bahloul Zouhir, Ayadi Hammadi

Abstract excerpt

Autoimmune diseases (AID) are caused by the loss of immunological tolerance against self-antigens. The deoxyribonuclease I (DNASE1) gene seems to participate in the genetic susceptibility of some AID. In fact, two mutations were reported among systemic lupus erythematosus (SLE) patients from Japan and Spain (the 172 A → T mutation (K5X) and the 46_72 deletion, respectively). The aim of our work was to evaluate...

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Identifiers

PMID: 19360410
DOI: 10.1007/s00296-009-0917-4

Genes

DNASE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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