Article
Interleukin 1 gene cluster, myocardial infarction at young age and inflammatory response of human mononuclear cells.
Immunological investigations - 1 Jan 2009
Latella Maria Carmela, de Gaetano Monica, Di Castelnuovo Augusto, Napoleone Emanuela, Lorenzet Roberto, Gattone Marinella, Giannuzzi Pantaleo, Rogus John, Huttner Kenneth, Donati Maria Benedetta, Iacoviello Licia
Abstract excerpt
The objective was to investigate whether genotypes, haplotypes and haplotype-pairs of interleukin (IL) gene cluster are associated with risk of Myocardial Infarction (MI) at young age and with the release of IL-1B and expression of tissue factor pro-coagulant activity (TFPCA), after stimulation in vitro with lipopolysaccharide (LPS) of human peripheral blood mononuclear cells (PBMCs). Patients with MI at young...
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