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Article

Resistance of CD1d-/- mice to ultraviolet-induced skin cancer is associated with increased apoptosis.

The American journal of pathology - 1 Sept 2004

Matsumura Yasuhiro, Moodycliffe Angus M, Nghiem Dat X, Ullrich Stephen E, Ananthaswamy Honnavara N

Abstract excerpt

Inhibition of p53-induced epidermal apoptosis, generation of p53 mutations, and suppressor T cells are the critical events responsible for the induction and development of UV-induced skin cancers. Recently, we demonstrated that CD1d knockout mice were resistant to UV-induced immunosuppression, prompting us to further address the role of CD1d in regulating UV carcinogenesis. We, therefore, investigated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15331412
DOI: 10.1016/S0002-9440(10)63350-0
PMCID: PMC1618602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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