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Differential Roles of T‐cell Subsets in Regulation of Ultraviolet Radiation Induced Cutaneous Photocarcinogenesis

12 Nov 2010

Abstract excerpt

Ultraviolet (UV) radiation, in particular the midwavelength range (UVB; 290-320 nm), is one of the most significant risk factors for the development of nonmelanoma skin cancer. UVB radiation-induced immunosuppression, which occurs in both humans and laboratory animals, contributes to their pathogenesis. However, there are conflicting reports on the relative role of CD4(+) and CD8(+) T cells in UVB induced skin...

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PMID: 21143237
DOI: 10.1111/j.1751-1097.2010.00859.x

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