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Article

Polarity proteins control ciliogenesis via kinesin motor interactions.

Current biology : CB - 24 Aug 2004

Fan Shuling, Hurd Toby W, Liu Chia-Jen, Straight Samuel W, Weimbs Thomas, Hurd Elizabeth A, Domino Steven E, Margolis Ben

Abstract excerpt

BACKGROUND: Cilia are specialized organelles that play a fundamental role in several mammalian processes including left-right axis determination, sperm motility, and photoreceptor maintenance. Mutations in cilia-localized proteins have been linked to human diseases including cystic kidney disease and retinitis pigmentosa. Retinitis pigmentosa can be caused by loss-of-function mutations in the polarity protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15324661
DOI: 10.1016/j.cub.2004.08.025

Genes

CRB1
CRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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