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Article

Crumbs homologue 1 in polarity and blindness.

Biochemical Society transactions - 1 Nov 2004

Meuleman J, van de Pavert S A, Wijnholds J

Abstract excerpt

Several retinal dystrophies, including retinitis pigmentosa type 12 and Leber congenital amaurosis, are caused by a large variety of mutations in the CRB1 (Crumbs homologue 1) gene. This discovery led to an increased focus on the function of CRB1 and the Drosophila homologue Crumbs. In the present study, we review the current knowledge on Crumbs and its vertebrate homologues, their function in cell polarity and...

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Source

Identifiers

PMID: 15494026
DOI: 10.1042/BST0320828

Genes

CRB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Crumbs homologue 1 in polarity and blindness.PMID 15494026Read ↗

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