Article
Analysis of subassemblies of pertussis toxin subunits in vivo and their interaction with the ptl transport apparatus.
Infection and immunity - 1 Sept 2004
Burns Drusilla L, Fiddner Stefanie, Cheung Anissa M, Verma Anita
Abstract excerpt
Pertussis toxin (PT) has an AB(5) structure that is typical of many bacterial protein toxins; however, this toxin is more complex than many toxins since it is composed of five different subunit types, subunits S1 to S5. Little is known about how PT assembles in vivo and how and when it interacts with its secretion apparatus, known as the Ptl transporter. In order to better understand these events, we expressed...
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