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Article

Pertussis toxin export requires accessory genes located downstream from the pertussis toxin operon.

Molecular microbiology - 1 May 1993

Covacci A, Rappuoli R

Abstract excerpt

Pertussis toxin, a major virulence factor of Bordetella pertussis, is an oligomeric protein composed of five different subunits that are exported individually to the periplasmic space by the signal peptide-dependent pathway. After assembly, the protein is exported from the periplasm to the extracellular compartment. We show that pertussis toxin secretion across the outer membrane requires the gene product of at...

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Identifiers

PMID: 8326857
DOI: 10.1111/j.1365-2958.1993.tb01587.x

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