Article
Pertussis toxin export requires accessory genes located downstream from the pertussis toxin operon.
Molecular microbiology - 1 May 1993
Covacci A, Rappuoli R
Abstract excerpt
Pertussis toxin, a major virulence factor of Bordetella pertussis, is an oligomeric protein composed of five different subunits that are exported individually to the periplasmic space by the signal peptide-dependent pathway. After assembly, the protein is exported from the periplasm to the extrac...
Topics
- Agrobacterium tumefaciens
- Amino Acid Sequence
- Bacterial Proteins
- Biological Transport
- Bordetella pertussis
- Genes, Bacterial
- Molecular Sequence Data
- Open Reading Frames
- Operon
- Pertussis Toxin
- Phenotype
- Protein Processing, Post-Translational
- Sequence Alignment
- Sequence Homology, Amino Acid
- Virulence Factors
- Virulence Factors, Bordetella