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Article

Mutations in the S1 subunit of pertussis toxin that affect secretion.

Infection and immunity - 1 Mar 2000

Craig-Mylius K A, Stenson T H, Weiss A A

Abstract excerpt

Pertussis toxin is a member of the AB(5) family of toxins and is composed of five subunits (S1 to S5) present in a 1:1:1:2:1 ratio. Secretion is a complex process. Each subunit has a secretion signal that mediates transport to the periplasm, where processing and assembly occur. Secretion of the assembled 105-kDa toxin past the outer membrane is mediated by the nine proteins encoded in the ptl operon. Previous...

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Source

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Identifiers

PMID: 10678938
DOI: 10.1128/IAI.68.3.1276-1281.2000
PMCID: PMC97279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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