Article
Comparison of DNA adduct levels in nasal mucosa, lymphocytes and bronchial mucosa of cigarette smokers and interaction with metabolic gene polymorphisms.
Carcinogenesis - 1 Dec 2004
Peluso Marco, Neri Monica, Margarino Giovanni, Mereu Carlo, Munnia Armelle, Ceppi Marcello, Buratti Marina, Felletti Raffaella, Stea Francesca, Quaglia Roberto, Puntoni Riccardo, Taioli Emanuela, Garte Seymour, Bonassi Stefano
Abstract excerpt
The recent introduction of biomarkers in population studies of lung cancer has improved the traditional epidemiological approach, especially in the detection of high risk groups. Many inhalable carcinogens form DNA adducts, an initial event in lung carcinogenesis, and therefore the identification of easily accessible sources of DNA for population studies is considered a leading priority in the field. In this...
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