Article
Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2006
Ketelslegers Hans B, Gottschalk Ralph W H, Godschalk Roger W L, Knaapen Ad M, van Schooten Frederik J, Vlietinck Robert F M H, Kleinjans Jos C S, van Delft Joost H M
Abstract excerpt
Genetic polymorphisms in genes involved in processes that affect DNA damage may explain part of the large interindividual variation in DNA adduct levels in smokers. We investigated the effect of 19 polymorphisms in 12 genes involved in carcinogen metabolism, DNA repair, and oxidant metabolism on...
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