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Article

Mice with deficiency of G protein gamma3 are lean and have seizures.

Molecular and cellular biology - 1 Sept 2004

Schwindinger William F, Giger Kathryn E, Betz Kelly S, Stauffer Anna M, Sunderlin Elaine M, Sim-Selley Laura J, Selley Dana E, Bronson Sarah K, Robishaw Janet D

Abstract excerpt

Emerging evidence suggests that the gamma subunit composition of an individual G protein contributes to the specificity of the hundreds of known receptor signaling pathways. Among the twelve gamma subtypes, gamma3 is abundantly and widely expressed in the brain. To identify specific functions and associations for gamma3, a gene-targeting approach was used to produce mice lacking the Gng3 gene (Gng3-/-)....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15314181
DOI: 10.1128/MCB.24.17.7758-7768.2004
PMCID: PMC506985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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