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Article

Disruption of G-protein γ5 subtype causes embryonic lethality in mice.

PloS one - 1 Jan 2014

Moon Anne M, Stauffer Anna M, Schwindinger William F, Sheridan Kathy, Firment Ashley, Robishaw Janet D

Abstract excerpt

Heterotrimeric G-proteins modulate many processes essential for embryonic development including cellular proliferation, migration, differentiation, and survival. Although most research has focused on identifying the roles of the various αsubtypes, there is growing recognition that similarly divergent βγ dimers also regulate these processes. In this paper, we show that targeted disruption of the mouse Gng5 gene...

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Identifiers

PMID: 24599258
DOI: 10.1371/journal.pone.0090970
PMCID: PMC3944967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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