Article
Phenotypic consequences of deletion of the gamma 3, alpha 5, or beta 3 subunit of the type A gamma-aminobutyric acid receptor in mice.
Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 1994
Culiat C T, Stubbs L J, Montgomery C S, Russell L B, Rinchik E M
Abstract excerpt
Three genes (Gabrg3, Gabra5, and Gabrb3) encoding the gamma 3, alpha 5, and beta 3 subunits of the type A gamma-aminobutyric acid receptor, respectively, are known to map near the pink-eyed dilution (p) locus in mouse chromosome 7. This region shares homology with a segment of human chromosome 15...
Topics
- Angelman Syndrome
- Animals
- Brain Chemistry
- Chromosome Mapping
- Homozygote
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Phenotype
- Protein Conformation
- RNA, Messenger
- Receptors, GABA-A
- Sequence Deletion