Article
Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.
Biochemical and biophysical research communications - 28 Feb 1992
von Weizsäcker E, Strathmann M P, Simon M I
Abstract excerpt
Heterotrimeric guanine nucleotide binding proteins transduce signals from cell surface receptors to intracellular effectors. The alpha subunit is believed to confer receptor and effector specificity on the G protein. This role is reflected in the diversity of genes that encode these subunits. The beta and gamma subunits are thought to have a more passive role in G protein function; biochemical data suggests that...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain Chemistry
- GTP-Binding Proteins
- Genetic Variation
- Mice
- Molecular Sequence Data
- Protein Conformation
- Sequence Homology, Nucleic Acid
- Signal Transduction