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Article

Interleukin-10 promoter single-nucleotide polymorphisms as markers for disease susceptibility and disease severity in leprosy.

Genes and immunity - 1 Nov 2004

Moraes M O, Pacheco A G, Schonkeren J J M, Vanderborght P R, Nery J A C, Santos A R, Moraes M E, Moraes J R, Ottenhoff T H M, Sampaio E P, Huizinga T W J, Sarno E N

Abstract excerpt

We have determined IL-10 promoter genotypes of five single-nucleotide polymorphisms (SNPs): T-3575A, A-2849G, C-2763A, -A-1082G and C-819T. The haplotype frequencies were defined in healthy subjects compared to leprosy patients, and analyzed for their occurrence in multi- (MB) vs paucibacillary (PB) as severe and mild forms of leprosy, respectively. Haplotypes defined by three SNP positions (-3575, -2849 and...

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Identifiers

PMID: 15306847
DOI: 10.1038/sj.gene.6364122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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