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Expanding the Genetic Insights Into Leprosy: An Updated Meta-Analysis of Interleukin-10 Variants.

International journal of immunogenetics - 1 Apr 2026

Veeraraghavan Jayakumar, Stephen Sharon Benita, Narasimhan Meenakshi, Kanakaraj Lakshmi

Abstract excerpt

This meta-analysis aims to evaluate the association between interleukin-10 (IL-10) -819 C/T (rs1800871), -592 C/A (rs1800872) and -1082 A/G (rs1800896) polymorphisms and leprosy susceptibility by analyzing multiple genetic models in the Asian and Caucasian populations. A systematic literature search was conducted in PubMed, Web of Science, Google Scholar and Embase (January 2001 to February 2025) following PRISMA...

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PMID: 41368682
DOI: 10.1111/iji.70031

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