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Article

Genetic variations and interactions in anti-inflammatory cytokine pathway genes in the outcome of leprosy: a study conducted on a MassARRAY platform.

The Journal of infectious diseases - 15 Oct 2011

Aggarwal Shweta, Ali Shafat, Chopra Rupali, Srivastava Amit, Kalaiarasan Ponnusamy, Malhotra Dheeraj, Gochhait Sailesh, Garg Vijay K, Bhattacharya S N, Bamezai Rameshwar N K

Abstract excerpt

BACKGROUND: Mycobacterium leprae is the etiologic pathogen that causes leprosy. The outcome of disease is dependent on the host genetic background. METHODS: We investigated the association of 51 single-nucelotide polymorphisms (SNPs) in anti-inflammatory cytokines (IL-10, TGFB1, IL-6, IL-4, and IL-13) and receptors (IL-10RA, IL-10RB, TGFBR1, TGFBR2, IL-6R, IL-4R, IL-5RA, IL-5RB, and IL-13RA1) with susceptibility...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21917900
DOI: 10.1093/infdis/jir516

Genes

TGFBR2
TGFB1
TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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