Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms and haplotype structures in genes for transforming growth factor beta1 and its receptors in familial and unselected breast cancers.

International journal of cancer - 20 Oct 2004

Jin Qianren, Hemminki Kari, Grzybowska Ewa, Klaes Rüdiger, Söderberg Magnus, Zientek Helena, Rogozinska-Szczepka Jadwiga, Utracka-Hutka Beata, Pamula Jolanta, Pekala Wioletta, Försti Asta

Abstract excerpt

Alterations in TGF-beta signaling appear to be associated with an altered risk of developing cancer, including breast cancer. We carried out a case-control study on 8 polymorphisms, including 5 in the TGF-beta1 gene (G-800A, C-509T, Leu10-->Pro, Arg25-->Pro and Thr263-->Ile), a polyalanine polymorphism (9A-->6A) in the TGF-betaRI gene and 2 (G-875A and A-364G) in the TGF-betaRII gene, using samples from 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activin Receptors, Type I
Share to Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to Receptor, Transforming Growth Factor-beta Type I

Share to Receptor, Transforming Growth Factor-beta Type II

Share to Receptors, Transforming Growth Factor beta

Share to Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 15305380
DOI: 10.1002/ijc.20370

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms and haplotype structures in genes for transforming growth factor beta1 and its receptors in familial and unselected breast cancers.PMID 15305380Read ↗

TGFBR1(*)6A and Int7G24A variants of transforming growth factor-beta receptor 1 in Swedish familial and sporadic breast cancer.Semantic proximity Read ↗

Functional impact of sequence variation in the promoter region of TGFB1.Semantic proximity Read ↗

Bioinformatic and functional analysis of TGFBR1 polymorphisms.Semantic proximity Read ↗

TGFB1 and TGFBR1 polymorphisms and breast cancer risk in the Nurses' Health Study.Semantic proximity Read ↗

TGF-β1 functional polymorphisms: a review.Semantic proximity Read ↗

Transforming growth factor-beta1 genotype in sporadic breast cancer patients from India: status of enhancer, promoter, 5'-untranslated-region and exon-1 polymorphisms.Semantic proximity Read ↗

Polymorphisms in the potential functional regions of the TGF-β 1 and TGF-β receptor genes and disease susceptibility in HBV-related hepatocellular carcinoma patients.Semantic proximity Read ↗

Novel single nucleotide polymorphisms in the 3'-UTR of the TGFbetaRI and TGFbetaRIII genes.Semantic proximity Read ↗

Transforming growth factor beta 1 (TGFβ1) polymorphisms and haplotype structures have dual roles in breast cancer pathogenesis.Semantic proximity Read ↗

Role of single nucleotide polymorphisms and haplotypes in BRCA1 in breast cancer: Czech case-control study.Semantic proximity Read ↗

TGFBR1 signaling and breast cancer.Semantic proximity Read ↗

The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.