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Polymorphisms in the potential functional regions of the TGF-β 1 and TGF-β receptor genes and disease susceptibility in HBV-related hepatocellular carcinoma patients.

Molecular carcinogenesis - 1 Oct 2012

Xin Zhenhui, Zhang Wei, Xu Aiqiang, Zhang Li, Yan Tao, Li Zhuo, Wu Xiaopan, Zhu Xilin, Ma Juan, Li Ke, Li Hui, Liu Ying

Abstract excerpt

Hepatocellular carcinoma (HCC) is a disease of multiple etiologies caused by the accumulation of genetic and epigenetic defects. Current evidence indicates that the transforming growth factor beta (TGF-β) signaling pathway has a significant impact on different cellular process. Members of the TGF-β superfamily (TGF-β1, the type I TGF-β receptor [TβRI], type II TGF-β receptor [TβRII], and type III TGF-β receptor])...

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PMID: 22290546
DOI: 10.1002/mc.21876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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